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Curious to find out if others were having a similar experience, I took to Instagram to poll my followers. The 2020 merry christmas should we have a drink a yes b a c b xmas ugly sweatshirt was both overwhelming and divided: I received a flood of messages, voice memos, and emails written (mostly by women) in either vehement opposition or enthusiastic favor of therapy in its remote incarnation. While sensitivity to light can be a trigger for some migraine sufferers, a recent University of Arizona study found that exposure to green light one to two hours a day can reduce the number of headache days per month by an average of 60%. It sounds counterintuitive, but isolated green light from devices such as the Allay lamp, which was developed by Harvard Medical School migraine researchers, has been shown to reduce photophobia, or light sensitivity, by generating certain electrical signals in the eye and brain.
Until recently, many drugs used by doctors for migraines were developed for other conditions, such as epilepsy. But in the 2020 merry christmas should we have a drink a yes b a c b xmas ugly sweatshirt in other words I will buy this past few years, the FDA has approved several new classes of targeted, effective drugs developed specifically for migraines. Even better, they have markedly fewer side effects than commonly used tryptamine-based drugs, also known as triptans, which have been prescribed since the early ’90s to relieve headaches but often come with major side effects such as nausea, insomnia, or hair loss. CGRP inhibitors, medications that block calcitonin gene-related peptide—a protein released by the brain during migraine attacks (and “a very ugly, cumbersome name,” says Gottschalk)—are among the most promising. Three of these prescription-only drugs—Aimovig, Ajovy, and Emgality—are taken monthly with an EpiPen–like shot; a fourth, Vyepti, is administered via I.V. by a doctor every three months. “These drugs produce great results, in much less time, with almost no side effects,” Gottschalk confirms. Nurtec and Ubrelvy, which are gepants—another new class of FDA-approved medication that also targets CGRP molecules—are formulated to turn off migraines in progress rather than prevent them. “They don’t have quite as much bang for the buck as, say, an injection of [the commonly used triptan] sumatriptan,” says Gottschalk. “But they’re well tolerated and can do a great job.”
